Sr./Principal Medical Science Liaison full_time NEW

QED Therapeutics, an affiliate of BridgeBio Pharma, focuses on developing targeted treatments for FGFR-driven skeletal dysplasias, particularly Achondroplasia. Achondroplasia is the most common form of genetically-driven short stature, which causes potentially debilitating medical complications. With our experimental therapeutic candidate, infigratinib, we seek to provide an option to children living with Achondroplasia and their families.
 
Our business is inspired by our values:

• PUT PATIENTS FIRST
• LET SCIENCE SPEAK
• EVERY MINUTE COUNTS
• THINK INDEPENDENTLY
• BE RADICALLY TRANSPARENT

FGFR=fibroblast growth factor receptor.

BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful medicines to patients. Founded in 2015, the company has built a portfolio of 30+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs.

Our focus on scientific excellence and rapid execution aims to translate today’s discoveries into tomorrow’s medicines. We have U.S. offices in San Francisco, Palo Alto, Raleigh, and with small satellites in other parts of the country. We also have international offices in Montreal, Canada, and Zug, Switzerland, and are expanding across Europe.

To learn more about our story and company culture, visit us at https://www.qedtx.com/ | https://bridgebio.com 

The Sr./Principal Medical Science Liaison (MSL) is a field-based scientific expert responsible for communicating with a variety of internal and external stakeholders, providing medical and scientific information on the appropriate utilization of therapy(s), and advancing therapeutic disease state knowledge. The Sr./Principal MSL is a core member of the Medical Affairs Team, leveraging a scientific approach aligned with medical affairs objectives and therapeutic area medical plans. 

The Sr./Principal MSL will be experienced, working in a fast-paced, highly collaborative environment, specifically with product launch planning, rare disorders, or underdiagnosed patient populations.  This includes developing and executing a comprehensive territory medical plan, attending conferences, delivering scientific presentations, and scientific exchange with physicians and other healthcare providers.  This role will be critical to cultivating relationships and establishing professional collaborations with academic researchers, therapeutic area leaders, relevant research centers, organizations, and clinical care teams.

This position reports to the Sr. Medical Director and will require extensive travel, sometimes involving weekends.

Assigned Territory focused responsibilities:

Territory Strategy and Planning

• Collaborate with Senior Medical Director in the development and execution of scientific plans within their territory to meet company-defined goals within corporate and regulatory guidelines for products both marketed and in development
• Lead the execution of Medical Affairs strategic plans in territory
• Maintain clinical/technical expertise in specific therapeutic areas; review scientific journals, attend scientific and key technical meetings in territory and share learnings with key stakeholders
• Serve as resource to the commercial team on scientific/market intelligence
• Proactively provide feedback on emerging clinical/competitive trends

Local Market key relationship, scientific knowledge and access development

• Identify and build advocacy with key investigators and key accounts to facilitate mutually beneficial research on infigratinib
• Develop field-based relationships with KOLs, HCPs, Clinics, etc. in support of strategic plans and may contribute to HCP strategies for multiple brands
• Develops, maintains and leverages strategic relationships with professional societies consistent with Medical Affairs goals
• Develops, maintains and leverages strategic relationships with scientific board of patient advocacy groups consistent with medical affairs goals
• Demonstrates advanced HCP development and relationship skills across differing HCP segments
• Takes the lead in identification of new HCP segments and opportunities for Medical Affairs engagement
• Act as primary source of scientific product knowledge in territory (question escalation from HCPs, Clinics, etc.)
• Deliver high quality scientific presentations on infigratinib to physicians and other key external customers
• Provide medical support for commercial efforts in support of infigratinib such as representing BridgeBio/QED and infigratinib at Medical Affairs booths during scientific symposia
• Assist in the management of territory KOLs / Investigators (IRs) involved in publications in collaboration with Medical Affairs stakeholders, as needed
• Recognize and share any key information received in field meetings that is critical to Medical strategy such as adverse events, safety issues, or other field intelligence
• Gather competitive intelligence and clinical insights from the field and provide to BridgeBio/QED competitive intelligence function and Medical Director indication lead

Post-Marketing Research – Registries, ISTs, observational

• Visit potential research sites to determine the site’s ability to conduct and accrue to clinical research studies and registries (i.e. patient volume, research experience, methodologies, competing studies, etc.)
• Implementation and coordination of independent research (investigator sponsored trials – ISTs) activities intended to support the clinical and scientific strategy for infigratinib
• Able to gain team and stakeholder alignment on research implications and facilitate cross-functional discussions on recommended actions
• Liaise with the Study Management and/or Clinical function by forwarding potential investigators for other BridgeBio/QED products in development
• Skilled in interpretation and application of clinical data
• Through peer education, enables other MSLs and stakeholders to build their data analysis and synthesis skills, and understand the implications of research results for the business
• Serves as a lead for clinical trial/research activities
• Support BridgeBio/QED sponsored clinical studies (Site Initiation Visit (SIV), Phase III trials) and registry (marketed) studies at sites in the territory by providing training, responding to inquiries, sharing feedback and new information, as appropriate

Product leadership responsibilities:

Product Strategy and Planning

• For an assigned product, collaborate with key stakeholders in the development of MSL product strategies in support of a Regional Medical Plan

Product / Scientific knowledge

• Develop and maintain thorough understanding of product and disease areas
• Demonstrate thorough understanding of BridgeBio/QED clinical and commercial priorities for product
• Collaborate with MDs and Medical Information on the development and maintenance of the infigratinib medical narrative decks which are used as a basis in responding to any unsolicited inquiries to MDs, MSLs and Medical Information
• Update and maintain MSL slide decks for use by MSL team based on content from approved product master slide decks; notify MSL team of any updates including global MSLs
• Helps to assess knowledge/skill gaps of others and provide developmental support as needed
• Provides guidance and coaching to others in developing and applying scientific and HCP insights
• Serves as an internal and external authority on the scientific and medical aspects of the business and industry
• Contributes to scientific literature and participates in scientific dialogue with external medical experts, and internal US and global medical teams
• Serves as point of reference and authority for the integration of science into proposed business strategies
• Guides team to use a standard approach for development and use of scientific materials that includes HCP and internal stakeholder perspectives
• Create and facilitate approval of pipeline slides covering each development compound and distribute to global MSL teams
• Handle product scientific question escalation from the field or territory leads
• Act as primary point of contact to gather escalated competitive intelligence, clinical insights and other key product information from field interactions or other MSLs in the region

Training

• Conduct product specific scientific training and field meetings with new hires, colleagues in Commercial and external stakeholders
• Assist in the training of new commercial recruits by presenting the scientific disease and product related data and present at sales conferences, regional meetings, etc. to develop high level of medical knowledge within sales force

Managed Markets and Healthcare System Knowledge

• Deep knowledge of current healthcare environment and implications to MEDICAL AFFAIRS
• Translates trends in managed markets space into possible strategies for MEDICAL AFFAIRS
• Applies knowledge of the current US Healthcare System to MEDICAL AFFAIRS
• Demonstrates broad knowledge and understanding of all aspects of the US Healthcare System and serves as a resource for US Medical Affairs
• Serves as the scientific resource the NAM team utilizes for deep scientific discussions with payers
• Acts as leader to provide field feedback for Managed Market objection handler / slide deck development

MSL Leadership (Principal MSL may have manager responsibilities)

• Support the Senior Medical Director in recruiting, hiring, promotions and team development and management efforts for MSL
• Collaborate with AD/Director, MSL efforts, in collaboration with HR, for all MSL staff in region including recruitment, development, leadership and staffing, budgeting, and the development of MSL objectives that are in alignment with BridgeBio/QED Global Medical Affairs objective

Career Development:

• BridgeBio/QED offers comprehensive career development programming, including guidance, targeted training opportunities, and mentorship programming. A career development pathway for MEDICAL AFFAIRS has been defined and is available to employees of BridgeBio/QED

People Management:

• The Principal/Sr. MSL will have management responsibilities (3-5 MSLs). This decision will be made in discussions with the Sr. Medical Director, and the Head of Medical Affairs

No matter your role at BridgeBio, successful team members are:

• Patient Champions, who put patients first and uphold strict ethical standards
• Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset
• Truth Seekers, who are detailed, rational, and humble problem solvers
• Individuals Who Inspire Excellence in themselves and those around them
• High-quality executors, who execute against goals and milestones with quality, precision, and speed

• Candidates with a PharmD, Ph.D., MD, Genetic Counseling, as well as other advanced healthcare degrees or relevant experience, will be considered
• 3+ years of medical affairs or field medical experience with a verifiable record of high performance is preferred, or at least 2 years of other relevant clinical or healthcare experience will be considered
• Prior experience in rare diseases and/or skeletal dysplasia is preferred
• Excellent interpersonal communication and presentation skills (including networking)
• Able to participate in a scientific dialogue with KOLs and researchers
• Excellent teaching skills and ability to present and discuss scientific material clearly and concisely
• Proven ability to create and sustain relationships with industry leaders
• Skilled in clinical research and an understanding of the process of pharmaceutical product development and approval
• Demonstrated ability to organize, prioritize, and work effectively with minimal supervision in a constantly changing environment
• Travel 50-60% of the time depending on territory size; evening and weekend work will be involved with some variation based upon the demands of the business imperatives

• Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts
• A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
• An unyielding commitment to always putting patients first. Learn more about how we do this here
• A de-centralized model that enables our program teams to focus on advancing science and helping patients. Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science
• A place where you own the vision – both for your program and your own career path
• A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
• Access to learning and development resources to help you get in the best professional shape of your life
• Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
• Flexible PTO
• Rapid career advancement for strong performers
• Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time 
• Partnerships with leading institutions
• Commitment to Diversity, Equity & Inclusion